Alterations in leukocyte telomere length in workers occupationally exposed to benzene
نویسندگان
چکیده
منابع مشابه
Alterations in leukocyte telomere length in workers occupationally exposed to benzene.
Exposure to benzene, a known leukemogen and probable lymphomagen, has been demonstrated to result in oxidative stress, which has previously been associated with altered telomere length (TL). TL specifically has been associated with several health outcomes in epidemiologic studies, including cancer risk, and has been demonstrated to be altered following exposure to a variety of chemical agents. ...
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Organophosphate chronic toxicity has been evaluated in this study. Biological screening for organophosphate insecticide-exposed workers is mostly recommended for mixers, loaders, formulators and spraymen. We have studied 17 occupationally exposed persons to pesticides. Using Ellman's colorimetric method, their plasma cholinesterase activities have been measured. Results show that the appear...
متن کاملNonrandom distribution of breakpoints in the karyotypes of workers occupationally exposed to benzene.
The distribution of the breakpoints in the karyotypes of workers occupationally exposed to benzene was tested. Fifty-six workers exposed to benzene were investigated cytogenetically. A significant increase in chromosome aberrations was observed. The distribution of the breakpoints in the karyotypes of examined workers was significantly nonrandom (p less than or equal to 0.001). The breakpoints ...
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BACKGROUND Nickel exposure is recognized as an endocrine disruptor because of its adverse effects on reproduction. AIM This study was designed to investigate the possible testiculo-hormonal perturbations on workers occupationally exposed to nickel and to assess its effects on human male sexual function. METHODS Cross-sectional comparative study, comprising 105 electroplating male non-smoker...
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As benzene has been linked with elevated risk of both acute myeloid leukemia and lymphoma, we explored the effect of benzene exposure on levels of t(8;21), t(15;17), and t(14;18) translocations. Circulating lymphocytes of normal individuals also often contain t(14;18). Quantitative polymerase chain reaction analysis showed that 37 workers with benzene exposure had a decreased level of t(14;18) ...
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ژورنال
عنوان ژورنال: Environmental and Molecular Mutagenesis
سال: 2014
ISSN: 0893-6692
DOI: 10.1002/em.21880